Please can anyone of the 400,000 IEEE members who received funding for a high spatial resolution PET to the detriment of sensitivity provide an answer consistent with science, based on analytical thinking, calculations and scientific evidence, on whether high spatial resolution in PET can save more lives than high sensitivity? Crosetto tried to ask this question at the 2014 IEEE-MIC Conference but the Deputy Chairman took the microphone away from him.
In 2014, Crosetto’s microphone was again taken away by the Deputy Chair of the IEEE-MIC Conference while asking a question to the MIC keynote speaker who presented a PET with sub-millimeter spatial resolution and very low sensitivity and efficiency in capturing signals from the tumor markers.
Crosetto pointed out that PET technique presented intrinsic errors of the path travelled by the positron before encountering an electron (from 1.4 mm to 13 mm) and the collinearity error that are affecting spatial resolution which are due to a natural phenomenon that cannot be eliminated.
Therefore, developing expensive electronics and crystal block detectors that cannot capture all signals from tumor markers is a disadvantage to the patient who receives high radiation and to the physician who cannot receive the information from the instrument related to the minimum abnormal metabolism.
The speaker answered that he was a chemist and was not aware of these nuclear phenomena. Crosetto asked if he would agree to have a public workshop within the conference where he and others could present their ideas and resolve this issue scientifically among scientists. (The issue if PET development should go in the direction of higher spatial resolution or higher sensitivity).
It was then that the microphone was taken away from Crosetto and the discussion interrupted before the speaker could answer. Later in the day Crosetto met the speaker and his team and realized they were satisfying the requirements of a pharmaceutical company whose primary interest was knowing the minimum shrinkage of the tumor resulting from the use of their drugs because that is a selling point, rather than concern for saving lives for the long term.
However, because the organizers of the IEEE-NSS-MIC-RTSD impeded Crosetto from further discussion during the public session, thousands of scientists participating at the conference were denied hearing the outcome of a dialogue among scientists that would have made the scientific truth for the benefit of humanity emerge.
This explains why it takes decades to change the trend of scientists focusing on improving spatial resolution to the detriment of sensitivity to improving PET sensitivity at the lowest cost per valid tumor marker captured.